proline

proline
(= pro; P; 115D)
One of the 20 amino acids directly coded for in proteins. Structure differs from all the others, in that its side chain is bonded to the nitrogen of the a -amino group, as well as the a -carbon. This makes the amino group a secondary amine, and so proline is described as an imino acid. Has strong influence on secondary structure of proteins and is much more abundant in collagens than in other proteins, occurring especially in the sequence glycine-proline hydroxyproline. A proline-rich region seems to characterize the binding site of SH3 domains.

Dictionary of molecular biology. 2004.

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Look at other dictionaries:

  • Proline — L ou S( ) proline   et   D ou R(+) proline …   Wikipédia en Français

  • proline — ● proline nom féminin Acide aminé non essentiel (qui peut être synthétisé par l organisme), présent en abondance dans les protéines. proline [pʀɔlin] n. f. ÉTYM. 1905, → cit.; all. Prolin dû à Fischer et Abderhalden, 1901. → cit. ❖ ♦ Chim., biol …   Encyclopédie Universelle

  • proline — [prō′lēn΄, prō′lin] n. [Ger prolin, contr. < pyrrolidin < pyrrol, PYRROLE + id, IDE + in, INE3] a nonessential amino acid, C4H8N COOH, formed by the decomposition of proteins: see AMINO ACID …   English World dictionary

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  • proline — Pyrrolidine 2 carboxylic acid; the l isomer is found in proteins, especially the collagens. SYN: pyrrolidine 2 carboxylate. p. aminopeptidase SYN: p. iminopeptidase. p. dehydrogenase SYN: pyrroline 2 carboxylate reductase, pyrroline 5 carboxylate …   Medical dictionary

  • proline — prolinas statusas T sritis chemija formulė NC₄H₈COOH santrumpa( os) Pro, P atitikmenys: angl. proline rus. пролин ryšiai: sinonimas – 2 pirolidinkarboksirūgštis …   Chemijos terminų aiškinamasis žodynas

  • Proline oxidase — Proline dehydrogenase (oxidase) 1, also known as PRODH, is a human gene.cite web | title = Entrez Gene: PRODH proline dehydrogenase (oxidase) 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=5625|… …   Wikipedia

  • ProLine (company) — ProLine is a range of own brand electronic products made by KESA Electricals plc for BCC in the Netherlands, Darty in France and Comet in the United Kingdom. ProLine covers a wide range of electricals across the store, covering white and brown… …   Wikipedia

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